If you are wearing a jacket, use your hand to sweep it out of the way and grip the butt of your gun as you would for shooting. If an untucked shirt covers the gun, clear it by grabbing the hem with your nonshooting hand and lifting it above the gun while the shooting hand grabs the weapon. A tucked shirt with an in the waistband will require an extra tug with the non shooting hand to free the hem of the shirt and lift it out of the way.
Use your thumb to open any flaps or snaps that hold the gun in the holster. Lift upward to clear the holster. Rotate the muzzle forward and upward until you reach shooting level, pointing at the target.